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2024, Vol: 14, Issue: 4
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Review Article 


Current trends and possible therapeutic options against COVID-19

Uzair Ahmed, Usman Ali Ashfaq, Saba Khaliq, Muhammad Qasim, Shah Jahan, Muhammad Shareef Masoud.


Cited By:2

Abstract
COVID-19 is a highly contagious disease, caused by SARS-CoV-2, which can be transmitted from person to person. SARS-CoV-2 has thought to be originated in bats and transmitted to humans. SARS-CoV-2 has ssRNA genome that is about 30kb in length and it enters lung epithelial cells using spikes (S) by binding with Angiotensin‐converting enzyme 2 (ACE-2). Till date, there is no definitive treatment available for COVID-19 and currently, only symptomatic treatments are available. There is no vaccine developed to combat COVID-19 but scientists are working on developing different types of vaccines including nucleic acid vaccines, subunit vaccines and whole virus vaccines, that are effective and safe to use. Broad spectrum antivirals like ribavirin, lopinavir, ritonavir, arbidol, favipiravir, remdesivir are being test to lessen the viral load. Recently, ivermectin (anti-parasitic drug), has been administered in vitro and showed 99.8% reduction in SARS-CoV-2 in cultured cells in 48 hours. Convalescent plasma (CP) treatments are also being used in order to treat critical cases, nevertheless, no drug has been approved yet. This review focuses on the transmission, clinical features, prevention, current treatments and future possible approaches that can be used to develop therapeutic options against COVID-19. J Microbiol Infect Dis 2019; 9(3):110-120.

Key words: SARS-CoV-2, clinical features, therapeutic options, antivirals, vaccines


 
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How to Cite this Article
Pubmed Style

Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbiol Infect Dis. 2020; 10(3): 110-120 . doi:10.5799/jmid.790198

Web Style

Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. https://www.jmidonline.org/?mno=302657394 [Access: January 09, 2025]. doi:10.5799/jmid.790198

AMA (American Medical Association) Style

Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbiol Infect Dis. 2020; 10(3): 110-120 . doi:10.5799/jmid.790198


Vancouver/ICMJE Style

Ahmed U, Ashfaq UA, Khaliq S, Qasim M, Jahan S, Masoud MS. Current trends and possible therapeutic options against COVID-19. J Microbiol Infect Dis. (2020), [cited January 09, 2025]; 10(3): 110-120 . doi:10.5799/jmid.790198


Harvard Style

Ahmed, U., Ashfaq, . U. A., Khaliq, . S., Qasim, . M., Jahan, . S. & Masoud, . M. S. (2020) Current trends and possible therapeutic options against COVID-19. J Microbiol Infect Dis, 10 (3), 110-120 . doi:10.5799/jmid.790198


Turabian Style

Ahmed, Uzair, Usman Ali Ashfaq, Saba Khaliq, Muhammad Qasim, Shah Jahan, and Muhammad Shareef Masoud. 2020. Current trends and possible therapeutic options against COVID-19. Journal of Microbiology and Infectious Diseases, 10 (3), 110-120 . doi:10.5799/jmid.790198


Chicago Style

Ahmed, Uzair, Usman Ali Ashfaq, Saba Khaliq, Muhammad Qasim, Shah Jahan, and Muhammad Shareef Masoud. "Current trends and possible therapeutic options against COVID-19." Journal of Microbiology and Infectious Diseases 10 (2020), 110-120 . doi:10.5799/jmid.790198


MLA (The Modern Language Association) Style

Ahmed, Uzair, Usman Ali Ashfaq, Saba Khaliq, Muhammad Qasim, Shah Jahan, and Muhammad Shareef Masoud. "Current trends and possible therapeutic options against COVID-19." Journal of Microbiology and Infectious Diseases 10.3 (2020), 110-120 . Print. doi:10.5799/jmid.790198


APA (American Psychological Association) Style

Ahmed, U., Ashfaq, . U. A., Khaliq, . S., Qasim, . M., Jahan, . S. & Masoud, . M. S. (2020) Current trends and possible therapeutic options against COVID-19. Journal of Microbiology and Infectious Diseases, 10 (3), 110-120 . doi:10.5799/jmid.790198


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Journal of Microbiology and Infectious Diseases (JMID) is an international "peer review" journal in microbiology, infectious diseases, virology, ... Read more.



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Journal of Microbiology and Infectious Diseases

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