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2024, Vol: 14, Issue: 3
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Research Article 


Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan.


Abstract
Objective: To screen HCV infection in HIV infected individuals and to compare the genotype and viral load of HCV in these co infected patients versus HIV negative individuals.
Methods: Serum samples from 70 HIV infected patients and 70 HIV negative individuals who enrolled in the ART center were retrospectively analyzed for the presence of anti HCV antibodies and for HCV RNA. Genotyping and viral load were further determined in HCV RNA positive patients.
Results: HCV infection (either positive for anti HCV Ab, or HCV RNA or both) was found in 8.57% HIV infected cases as compared to 2.85% individuals in the HIV uninfected control group. HCV RNA levels were higher in HIV infected subjects versus HIV negative individuals. Among the HIV positive cases, out of the three HCV RNA positive cases, two individuals had genotype 3 and one individual was found to have mixed genotype (1+3) as compared to genotype 1 and genotype 3 in HIV negative healthy controls.
Conclusion: In our study, HCV infection was found more frequently in HIV infected individuals as compared to HIV non infected individuals. Therefore a routine screening test followed by a confirmatory test should be made mandatory in co infected patients. J Microbiol Infect Dis 2017; 7(4):167-172


 
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How to Cite this Article
Pubmed Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. J Microbiol Infect Dis. 2017; 7(4): 167-172 . doi:10.5799/jmid.368504

Web Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. https://www.jmidonline.org/?mno=302657125 [Access: November 22, 2024]. doi:10.5799/jmid.368504

AMA (American Medical Association) Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. J Microbiol Infect Dis. 2017; 7(4): 167-172 . doi:10.5799/jmid.368504


Vancouver/ICMJE Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. J Microbiol Infect Dis. (2017), [cited November 22, 2024]; 7(4): 167-172 . doi:10.5799/jmid.368504


Harvard Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan (2017) Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. J Microbiol Infect Dis, 7 (4), 167-172 . doi:10.5799/jmid.368504


Turabian Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. 2017. Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. Journal of Microbiology and Infectious Diseases, 7 (4), 167-172 . doi:10.5799/jmid.368504


Chicago Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. "Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis." Journal of Microbiology and Infectious Diseases 7 (2017), 167-172 . doi:10.5799/jmid.368504


MLA (The Modern Language Association) Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan. "Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis." Journal of Microbiology and Infectious Diseases 7.4 (2017), 167-172 . Print. doi:10.5799/jmid.368504


APA (American Psychological Association) Style

Parul Punia, Anita Chakravarti, Anjar Ashraf, Preena Bhalla, Richa Dewan (2017) Epidemiology of Hepatitis C Virus and Human Immunodeficiency Virus Co-infection and Challenges in Their Diagnosis. Journal of Microbiology and Infectious Diseases, 7 (4), 167-172 . doi:10.5799/jmid.368504


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Journal of Microbiology and Infectious Diseases

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