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2024, Vol: 14, Issue: 3
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Case Report 


Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti.


Abstract
The frequency of invasive fungal infections in patients with hematological malignancies has dramatically increased over the last two decades mainly due to increased use of more intensive therapies. Trichosporon spp is an uncommon but frequently fatal invasive yeast infection that occur predominantly in patients with hematological malignancies. Trichosporon Asahii (T. Asahii) is the most common genus isolated and is reported to cause serious invasive infections in adults and infrequently in children. Voriconazole (VCZ) remains the antifungal drug of choice. We report six pediatric patients with acute lymphoblastic leukemia (2), acute myeloblastic leukemia (2), lymphoblastic lymphoma (1) who developed invasive T. Asahii infection during the early phases of CTR. The outcome was poor. Five patients have died as a result of the infection after a stormy clinical course and prolonged stay in the pediatric intensive care unit despite receiving proper antifungal treatment. Only one patient survived the infection without serious sequalae. J Microbiol Infect Dis 2020; 8(3):167-172.

Key words: Amphotericin B, Caspofungin, Invasive fungal infections, Trichosporon Asahii, Voriconazole


 
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How to Cite this Article
Pubmed Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. J Microbiol Infect Dis. 2020; 10(3): 167-172 . doi:10.5799/jmid.790293

Web Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. https://www.jmidonline.org/?mno=302657227 [Access: November 22, 2024]. doi:10.5799/jmid.790293

AMA (American Medical Association) Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. J Microbiol Infect Dis. 2020; 10(3): 167-172 . doi:10.5799/jmid.790293


Vancouver/ICMJE Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. J Microbiol Infect Dis. (2020), [cited November 22, 2024]; 10(3): 167-172 . doi:10.5799/jmid.790293


Harvard Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti (2020) Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. J Microbiol Infect Dis, 10 (3), 167-172 . doi:10.5799/jmid.790293


Turabian Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. 2020. Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. Journal of Microbiology and Infectious Diseases, 10 (3), 167-172 . doi:10.5799/jmid.790293


Chicago Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. "Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.." Journal of Microbiology and Infectious Diseases 10 (2020), 167-172 . doi:10.5799/jmid.790293


MLA (The Modern Language Association) Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti. "Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.." Journal of Microbiology and Infectious Diseases 10.3 (2020), 167-172 . Print. doi:10.5799/jmid.790293


APA (American Psychological Association) Style

Adil Abdelhamed Abbas, Abdulfattah Wasel Alamri, Areej Hasan Almofti (2020) Trichosporon Asahii Infection Mortality in Pediatric Oncology Patients. A Report of Six Cases.. Journal of Microbiology and Infectious Diseases, 10 (3), 167-172 . doi:10.5799/jmid.790293


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