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Research Article 


Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures

Şerife Altun, Hatice Uludağ Altun, Çiğdem Ataman Hatipoğlu, Cemal Bulut, Sami Kınıklı, Ali Pekcan Demiröz.


Cited By:2

Abstract
Objective: Vancomycin resistant enterococci (VRE) are important healthcare associated multidrug resistant organisms because of their easily spread in the hospital environment, difficulty to cure and high mortality rate. The aim of this study was to evaluate in vitro activity of daptomycin and tigecycline against VRE strains isolated from rectal swab samples of hospitalized patients.
Methods: Sixty non-duplicate VRE strains isolated from rectal swabs of hospitalized patients between October 2010 and February 2013 at Ankara Training and Research Hospital were included into the study. Ankara Training and Research Hospital in Ankara in Turkey is a 600 bed, tertiary care, teaching hospital. Minimum inhibitory concentration (MIC) values of daptomycin and tigecycline were determined by E-test method (bioMerieux, France).
Results: All of the strains were susceptible to daptomycin, three of them (5%) were resistant to tigecycline. MIC50 and MIC90 values of daptomycin were 1.5 µg/ml and 2 µgr/ml, and of tigecycline were 0.64 µg/ml and 0.125 µg/ml, respectively.
Conclusion: As a result; all of the strains were susceptible to daptomycin. On the other hand, resistance to tigecycline was exhibited by 5% of VRE isolates. Clinicians should be aware of the possibility of the emergence of tigecycline nonsusceptibility and should closely monitor tigecycline MICs of enterococci. J Microbiol Infect Dis 2014; 4(3): 87-90


 
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How to Cite this Article
Pubmed Style

Altun Å, Altun HU, HatipoÄŸlu CA, Bulut C, Kınıklı S, Demiroz AP. Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. J Microbiol Infect Dis. 2014; 4(3): 107-110 . doi:10.5799/jmid2014.03.0149

Web Style

Altun Å, Altun HU, HatipoÄŸlu CA, Bulut C, Kınıklı S, Demiroz AP. Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. https://www.jmidonline.org/?mno=302657153 [Access: January 09, 2025]. doi:10.5799/jmid2014.03.0149

AMA (American Medical Association) Style

Altun Å, Altun HU, HatipoÄŸlu CA, Bulut C, Kınıklı S, Demiroz AP. Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. J Microbiol Infect Dis. 2014; 4(3): 107-110 . doi:10.5799/jmid2014.03.0149


Vancouver/ICMJE Style

Altun Å, Altun HU, HatipoÄŸlu CA, Bulut C, Kınıklı S, Demiroz AP. Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. J Microbiol Infect Dis. (2014), [cited January 09, 2025]; 4(3): 107-110 . doi:10.5799/jmid2014.03.0149


Harvard Style

Altun, Å., Altun, . H. U., HatipoÄŸlu, . C. A., Bulut, . C., Kınıklı, . S. & Demiroz, . A. P. (2014) Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. J Microbiol Infect Dis, 4 (3), 107-110 . doi:10.5799/jmid2014.03.0149


Turabian Style

Altun, Şerife, Hatice Uludağ Altun, Ciğdem Ataman Hatipoğlu, Cemal Bulut, Sami Kınıklı, and Ali Pekcan Demiroz. 2014. Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. Journal of Microbiology and Infectious Diseases, 4 (3), 107-110 . doi:10.5799/jmid2014.03.0149


Chicago Style

Altun, Şerife, Hatice Uludağ Altun, Ciğdem Ataman Hatipoğlu, Cemal Bulut, Sami Kınıklı, and Ali Pekcan Demiroz. "Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures." Journal of Microbiology and Infectious Diseases 4 (2014), 107-110 . doi:10.5799/jmid2014.03.0149


MLA (The Modern Language Association) Style

Altun, Şerife, Hatice Uludağ Altun, Ciğdem Ataman Hatipoğlu, Cemal Bulut, Sami Kınıklı, and Ali Pekcan Demiroz. "Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures." Journal of Microbiology and Infectious Diseases 4.3 (2014), 107-110 . Print. doi:10.5799/jmid2014.03.0149


APA (American Psychological Association) Style

Altun, Å., Altun, . H. U., HatipoÄŸlu, . C. A., Bulut, . C., Kınıklı, . S. & Demiroz, . A. P. (2014) Daptomycin and Tigecycline Susceptibility of Vancomycin Resistant Enterococci Isolated from Rectal Swab Cultures. Journal of Microbiology and Infectious Diseases, 4 (3), 107-110 . doi:10.5799/jmid2014.03.0149


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Journal of Microbiology and Infectious Diseases

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