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2024, Vol: 14, Issue: 3
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Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic

Oktaviani Naulita Turnip, Chairunnisa Fadhillah, Anwar Rovik, Ayu Rahayu.


Cited By:1

Abstract
Objectives:
This study aims to understand the epidemiological features and level of genetic similarity in the SARS-CoV-2 from different geographical areas in The Southeast Asia Region during an early pandemic.
Methods:
The data on COVID-19 cases in Southeast Asia was collected from https://worldometer.info/ and extracted independently. Complete genome SARS-CoV-2 nucleotide sequence data was obtained from GISAID and NCBI online platforms. The sequences were aligned using MEGA X software and identified RdRp and Spike genes using UGENE software. The phylogenetic was constructed using MEGA X software to know the similarity of these genes among isolates in the Southeast Asia region.
Results:
The result showed that the first case in Southeast Asia was reported in January 2020. The highest number of COVID-19 cases and death were reported from populous and suffering countries. The phylogenetic results showed an identical solid (100%) among isolates, except for the Philippines-5 isolate. The Wuhan-Hu-1 (China) SARS-CoV-2 isolate (Acc. NC_045512) was transmitted to other countries in Southeast Asia region with various mutations in the spike protein.
Conclusion:
During the early pandemic, all countries in the Southeast Asia region reported COVID-19 cases. Indonesia became the country with the highest number of COVID-19 cases and deaths. The level of similarity of the RdRp gene in the SARS-CoV-2 in Southeast Asia is higher than the Spike genes.

Key words: Epidemiology, Phylogeny, SARS-Cov-2, Pandemic


 
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How to Cite this Article
Pubmed Style

Turnip ON, Fadhillah C, Rovik A, Rahayu A. Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. J Microbiol Infect Dis. 2022; 12(4): 139-147. doi:10.5799/jmid.1218631

Web Style

Turnip ON, Fadhillah C, Rovik A, Rahayu A. Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. https://www.jmidonline.org/?mno=302657116 [Access: November 23, 2024]. doi:10.5799/jmid.1218631

AMA (American Medical Association) Style

Turnip ON, Fadhillah C, Rovik A, Rahayu A. Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. J Microbiol Infect Dis. 2022; 12(4): 139-147. doi:10.5799/jmid.1218631


Vancouver/ICMJE Style

Turnip ON, Fadhillah C, Rovik A, Rahayu A. Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. J Microbiol Infect Dis. (2022), [cited November 23, 2024]; 12(4): 139-147. doi:10.5799/jmid.1218631


Harvard Style

Turnip, O. N., Fadhillah, . C., Rovik, . A. & Rahayu, . A. (2022) Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. J Microbiol Infect Dis, 12 (4), 139-147. doi:10.5799/jmid.1218631


Turabian Style

Turnip, Oktaviani Naulita, Chairunnisa Fadhillah, Anwar Rovik, and Ayu Rahayu. 2022. Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. Journal of Microbiology and Infectious Diseases, 12 (4), 139-147. doi:10.5799/jmid.1218631


Chicago Style

Turnip, Oktaviani Naulita, Chairunnisa Fadhillah, Anwar Rovik, and Ayu Rahayu. "Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic." Journal of Microbiology and Infectious Diseases 12 (2022), 139-147. doi:10.5799/jmid.1218631


MLA (The Modern Language Association) Style

Turnip, Oktaviani Naulita, Chairunnisa Fadhillah, Anwar Rovik, and Ayu Rahayu. "Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic." Journal of Microbiology and Infectious Diseases 12.4 (2022), 139-147. Print. doi:10.5799/jmid.1218631


APA (American Psychological Association) Style

Turnip, O. N., Fadhillah, . C., Rovik, . A. & Rahayu, . A. (2022) Epidemiological Features and Phylogeny of SARS-CoV-2 Circulating in the Southeast Asia in Early Pandemic. Journal of Microbiology and Infectious Diseases, 12 (4), 139-147. doi:10.5799/jmid.1218631


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