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Research Article 


Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli

Dara Agusti Maulidya, Muhammad Ibnu Kahtan, Diana Natalia, Mitra Handini, Ari Widiyantoro.

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Abstract
Objectives: Helminth infection is one of the main matters that cause health problems in developing countries. Polygonum minus are empirically used as an anthelmintic drug, but there has been no scientific study that proves it.
Methods: This study was aimed at determining the anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli in vitro. The extract was prepared in three different concentrations i.e 0.5 mg/mL, 1 mg/mL and 2 mg/mL. NaCl 0.9% was used as a negative control group and albendazole 0.2 mg/mL, a broad spectrum anthelmintic was used as a positive control group. Ascaridia galli was used as the test parasite. The study involved the determination of death time of the worms.
Results: The death time of the worms that caused by the extract concentration 0.5 mg/mL, 1 mg/mL and 2 mg/mL, respectively were (mean±SD) 35±3.32 hours, 32.8±2.39 hours and 25±3.39 hours. The death time that caused by negative and positive control group were 76.6±8.30 hours and 19.2±1.48 hours. There is no significant difference of death time of the worms between the extract concentration 2 mg/mL and the positive control group.
Conclusion: The anthelmintic activity of ethanol extract of Polygonum minus leaves has been confirmed and extract concentration 2 mg/mL has the same anthelmintic activity with albendazole 0.2 mg/mL. J Microbiol Infect Dis 2018; 8(1):23-26

Key words: Anthelmintic, Polygonum minus, Ascaridia galli, ascariasis


 
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How to Cite this Article
Pubmed Style

Maulidya DA, Kahtan MI, Natalia D, Handini M, Widiyantoro A. Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. J Microbiol Infect Dis. 2018; 8(1): 23-26 . doi:10.5799/jmid.403142

Web Style

Maulidya DA, Kahtan MI, Natalia D, Handini M, Widiyantoro A. Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. https://www.jmidonline.org/?mno=302657005 [Access: January 09, 2025]. doi:10.5799/jmid.403142

AMA (American Medical Association) Style

Maulidya DA, Kahtan MI, Natalia D, Handini M, Widiyantoro A. Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. J Microbiol Infect Dis. 2018; 8(1): 23-26 . doi:10.5799/jmid.403142


Vancouver/ICMJE Style

Maulidya DA, Kahtan MI, Natalia D, Handini M, Widiyantoro A. Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. J Microbiol Infect Dis. (2018), [cited January 09, 2025]; 8(1): 23-26 . doi:10.5799/jmid.403142


Harvard Style

Maulidya, D. A., Kahtan, . M. I., Natalia, . D., Handini, . M. & Widiyantoro, . A. (2018) Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. J Microbiol Infect Dis, 8 (1), 23-26 . doi:10.5799/jmid.403142


Turabian Style

Maulidya, Dara Agusti, Muhammad Ibnu Kahtan, Diana Natalia, Mitra Handini, and Ari Widiyantoro. 2018. Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. Journal of Microbiology and Infectious Diseases, 8 (1), 23-26 . doi:10.5799/jmid.403142


Chicago Style

Maulidya, Dara Agusti, Muhammad Ibnu Kahtan, Diana Natalia, Mitra Handini, and Ari Widiyantoro. "Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli." Journal of Microbiology and Infectious Diseases 8 (2018), 23-26 . doi:10.5799/jmid.403142


MLA (The Modern Language Association) Style

Maulidya, Dara Agusti, Muhammad Ibnu Kahtan, Diana Natalia, Mitra Handini, and Ari Widiyantoro. "Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli." Journal of Microbiology and Infectious Diseases 8.1 (2018), 23-26 . Print. doi:10.5799/jmid.403142


APA (American Psychological Association) Style

Maulidya, D. A., Kahtan, . M. I., Natalia, . D., Handini, . M. & Widiyantoro, . A. (2018) Anthelmintic activity of ethanol extract of Polygonum minus leaves against Ascaridia galli. Journal of Microbiology and Infectious Diseases, 8 (1), 23-26 . doi:10.5799/jmid.403142


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